---
product_id: 32721076
title: "SPM Active - Specialized Pro-Resolving Mediators from Marine Oils - Supports Normal Inflammatory Response, Tissue Health, Joint Comfort, Immune Health - Non-GMO, Gluten-Free - 120 Softgels"
brand: "metagenics"
price: "$995359"
currency: COP
in_stock: true
reviews_count: 8
category: "Metagenics"
url: https://www.desertcart.co/products/32721076-spm-active-specialized-pro-resolving-mediators-from-marine-oils-supports
store_origin: CO
region: Colombia
---

# Marine oil-derived SPMs for inflammation Supports joint & tissue resilience Boosts immune & cardiovascular health SPM Active - Specialized Pro-Resolving Mediators from Marine Oils - Supports Normal Inflammatory Response, Tissue Health, Joint Comfort, Immune Health - Non-GMO, Gluten-Free - 120 Softgels

**Brand:** metagenics
**Price:** $995359
**Availability:** ✅ In Stock

## Summary

> 🌟 Unlock your body's natural power to resolve inflammation and thrive!

## Quick Answers

- **What is this?** SPM Active - Specialized Pro-Resolving Mediators from Marine Oils - Supports Normal Inflammatory Response, Tissue Health, Joint Comfort, Immune Health - Non-GMO, Gluten-Free - 120 Softgels by metagenics
- **How much does it cost?** $995359 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.co](https://www.desertcart.co/products/32721076-spm-active-specialized-pro-resolving-mediators-from-marine-oils-supports)

## Best For

- metagenics enthusiasts

## Why This Product

- Trusted metagenics brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Clean, Trusted Quality:** Non-GMO, gluten-free softgels crafted in GMP-certified facilities with rigorous third-party purity testing.
- • **Immune & Heart Health Ally:** Omega-3 derived mediators support balanced immune response and cardiovascular wellness.
- • **Active Joint & Tissue Support:** Eases post-exercise discomfort while enhancing mobility and tissue durability for your busy lifestyle.
- • **Clinician-Recommended Excellence:** From the #1 doctor-recommended professional supplement brand, ensuring clinically proven, precision-crafted wellness.
- • **Precision Inflammation Resolution:** Harnesses specialized pro-resolving mediators (SPMs) to naturally calm inflammation and promote recovery.

## Overview

Metagenics SPM Active delivers specialized pro-resolving mediators sourced from marine oils to support normal inflammatory response, joint comfort, tissue health, and immune function. This non-GMO, gluten-free formula is manufactured under strict GMP standards and is highly recommended by healthcare professionals for natural, effective wellness support.

## Description

Buy Metagenics SPM Active - Specialized Pro-Resolving Mediators from Marine Oils - Supports Normal Inflammatory Response, Tissue Health, Joint Comfort, Immune Health - Non-GMO, Gluten-Free - 120 Softgels on desertcart.com ✓ FREE SHIPPING on qualified orders

Review: Wonderful alternative to harmful drugs - These supplements although they are not cheap, work great on inflammation! I have a rare autoimmune issue and have prescription medicine that I take for the condition. Since my functional medicine Dr recommended this product, I’ve been able to use this and cut down on the prescription medicine. Well worth the money and it’s a natural substance which is so much better for the body!
Review: Natural product - I would highly reccomend this product for joint pain, a natural way to help relieve joint issues.

## Features

- Targeted SPM Support: Provides specialized pro-resolving mediators (SPMs) from marine oils to support the body's natural resolution of the inflammatory response*
- Supports Joint & Tissue Health: Helps ease minor discomfort after exercise, supports mobility, and supports overall tissue health and resilience*
- Immune & Cardiovascular Benefits: Research on SPMs suggests support for healthy immune activity and cardiovascular function through omega-3 derived mediators*
- Clean and Trusted Formula: Non-GMO and gluten-free softgels, manufactured in GMP-certified facilities with rigorous third-party testing for purity and potency*
- As the #1 Doctor Recommended Professional Supplement Brand, Metagenics delivers clinically proven, precision-crafted formulas to support your health at its core because true wellness starts with integrity, balance, and expertise

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B01JVD0SK8 |
| Best Sellers Rank | #12,650 in Health & Household ( See Top 100 in Health & Household ) #515 in Blended Vitamin & Mineral Supplements #1,162 in Vitamin Supplements |
| Customer Reviews | 4.5 4.5 out of 5 stars (719) |
| Date First Available  | August 6, 2016 |
| Is Discontinued By Manufacturer  | No |
| Manufacturer  | Metagenics |
| Product Dimensions  | 2.41 x 2.41 x 4.5 inches; 5.8 ounces |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** Metagenics
- **Diet Type:** Gluten Free
- **Flavor:** Unflavored
- **Item Form:** Softgel
- **Item Weight:** 5.8 Ounces
- **Item dimensions L x W x H:** 2.41 x 2.41 x 4.5 inches
- **Product Benefits:** Tissue Health and Immune Support
- **Special Ingredients:** Marine Lipid Concentrate
- **Unit Count:** 120 Count

## Images

![SPM Active - Specialized Pro-Resolving Mediators from Marine Oils - Supports Normal Inflammatory Response, Tissue Health, Joint Comfort, Immune Health - Non-GMO, Gluten-Free - 120 Softgels - Image 1](https://m.media-amazon.com/images/I/71eSYPJNepL.jpg)

## Questions & Answers

**Q: Can I see the product label?  I need to know the amount of the active ingredient in each capsule.**
A: Hi,   It says 500 mg Active Fractionated Marine Lipid Concentrate (18 hydroxy eicosapentaenoic acid  (18-HEPE) and 17 hydroxy -docosahexanoic acid (17HDHA).
I had to look through a magnifying glass to see the words, a bit small for me, so the spelling may not be perfect!   I get this through my Holistic Doc and pay  $119.00.  $179.00 at Amazon seems a bit much.  Hope this has helped.

**Q: Has this product been tested for heavy metals?**
A: Please contact Metagenics.  They are very good about addressing this type of question.   I must say that several of the questions on the product are better addressed by the manufacturer.  I've found them to be very helpful.

**Q: why do these smell and taste like perfume and soap rolled up in one?? Frankly I would rather taste fish oil.**
A: there shouldn't be any smell to the product like you're describing.  I'd suggest you get in touch with the vendor about this.

**Q: Does this have soy in it?  The mixed trocophenols?**
A: all the ingredients are listed on their website or you can call them if you're not sure.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Wonderful alternative to harmful drugs
*by D***A on December 29, 2025*

These supplements although they are not cheap, work great on inflammation! I have a rare autoimmune issue and have prescription medicine that I take for the condition. Since my functional medicine Dr recommended this product, I’ve been able to use this and cut down on the prescription medicine. Well worth the money and it’s a natural substance which is so much better for the body!

### ⭐⭐⭐⭐⭐ Natural product
*by B***R on December 11, 2025*

I would highly reccomend this product for joint pain, a natural way to help relieve joint issues.

### ⭐⭐⭐⭐⭐ Great price
*by J***T on December 18, 2025*

Great price

## Frequently Bought Together

- Metagenics SPM Active - Specialized Pro Resolving Mediators for Joint Comfort, Tissue Health & Minor Discomfort Relief* - Non-GMO - Gluten Free - 120 Softgels
- Metagenics Vitamin D3 + K - for Immune Support, Bone Health & Heart Health* - Vitamin D with MK-7 (Vitamin K2) - Non-GMO - Gluten-Free - 60 Softgels - 10,000 IU
- Designs for Health Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (120 Capsules)

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---

*Product available on Desertcart Colombia*
*Store origin: CO*
*Last updated: 2026-01-28*