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Description

  • GeneName: NAMPT; VF; PBEF; PBEF1; VISFATIN; MGC117256; DKFZp666B131; 1110035O14Rik.
  • pre-B cell enhancing factor; Nicotinamide phosphoribosyltransferase.
  • nicotinamide phosphoribosyltransferase; NAmPRTase; OTTHUMP00000179149; OTTHUMP00000179150.
  • pre-B cell-enhancing factor; pre-B-cell colony enhancing factor 1.
  • Clonality: Monoclonal; *Isotype: IgG1; *Clone: 10B2534; *Source: Host: Mouse; Source: Human.
  • Reactivity: Human; *Tested: ELISA (EL/EIA), Western Blot (WB).
  • Form: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide..
  • Purity: Affinity Purified Purified by Protein G affinity chromatography..
  • Hybridoma: FO myeloma cells with spleen cells from Balb/c mice..
  • FREE-8GB-USBDrive for this item. Item is for research use. NOT for diagnostic/therapeutic procedure..
  • Imported from USA.
SynName: Anti -PBEF (Pre-B cell Colony Enhancing Factor, Pre-B cell Enhancing Factor, 1110035O14Rik, DKFZP666B131, EC 2.4.2.12, MGC117256, Nicotinamide Phosphoribosyltransferase, NAmPRTase, NAMPT, Pre-B cell Colony Enhancing Factor 1, PBEF1, Visfatin); PBEF (Pre-B cell Colony Enhancing Factor, Pre-B cell Enhancing Factor, 1110035O14Rik, DKFZP666B131, EC 2.4.2.12, MGC117256, Nicotinamide Phosphoribosyltransferase, NAmPRTase, NAMPT, Pre-B cell Colony Enhancing Factor 1, PBEF1, Visfatin); *AppNotes: Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1:1000-1:3000. Detectes a band of ~56kD in 293T cell lysates.; *Specificity: Recognizes human Visfatin.Immunogen: Recombinant corresponding to aa1-491 of human PBEF expressed in E. coli.; *Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. ; *Accession#: P43490; *Description: PBEF is a putative cytokine determined to be a nicotinamide phosphoribosyltransferase (NAMPT) enzyme and member of the NAPRTase family, involved in catalyzing the biosynthesis of NAD from nicotinamide. PBEF is highly expressed in bone marrow, muscle and liver tissue and increases in expression in response to endotoxin, in amniotic epithelial cells following lipopolysaccharide (LPS) stimulation, and during the activation of T and B cells, dendritic cells and macrophages, suggesting a role in inflammatory processes.; *NCBI Summary: This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolis...
Reviews

PBEF (Pre-B cell Colony Enhancing Factor, Pre-B cell Enhancing Factor, 1110035O14Rik, DKFZP666B13...

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