

🐾 Stay ahead of fleas—because your dog deserves the best defense!
Advantage II Large Dog Flea Treatment is a vet-recommended, topical solution designed for dogs weighing 21-55 lbs. It kills adult fleas, larvae, and eggs within 12 hours and provides 30 days of continuous protection. The fragrance-free, waterproof formula is easy to apply without a prescription, ensuring your dog stays flea-free and comfortable all month long.












| ASIN | B004QRFJA4 |
| ASIN | B004QRFJA4 |
| Active Ingredients | Imidacloprid, Pyriproxyfen |
| Age Range Description | 7 weeks and older |
| Allergen Information | Allergen-Free |
| Best Sellers Rank | #2,028 in Pet Supplies ( See Top 100 in Pet Supplies ) #14 in Dog Flea Drops |
| Brand Name | Advantage |
| Customer Reviews | 4.5 4.5 out of 5 stars (19,100) |
| Date First Available | March 5, 2011 |
| Department | Flea & Tick |
| Dog Breed Size | Large |
| Global Trade Identification Number | 00724089202833 |
| Is Discontinued By Manufacturer | No |
| Item Form | Topical |
| Item Type Name | Bayer Advantage II Flea and Lice Treatment for Large Dogs, 21-55 lb, 4 doses (Packaging may vary) |
| Item Weight | 0.04 Pounds |
| Item model number | 86336707 |
| Manufacturer | Elanco US Inc |
| Manufacturer | Elanco US Inc |
| Manufacturer Part Number | 86336707 |
| Manufacturer recommended age | 1 month and up |
| Model Number | 86336707 |
| Product Dimensions | 6.5 x 1 x 4.25 inches; 0.63 ounces |
| Scent Name | Unscented |
| Target Species | Dog |
| UPC | 724089202833 |
| Unit Count | 4 Count |
| Volume | 10 Milliliters |
B**Y
It's effective without being too potent
I've been using this for years. It works pretty good. It's becoming less and less effective as the fleas evolve to it. But right now it's still pretty effective.
M**S
A Helpful Tool In Our Flea Control Regimen!
We have double coated, long haired, very furry large Northern Breed Mixed Dogs. Unfortunately, fleas are a year round problem here in the San Francisco Bay Area where we live ... Ugh! Advantage II Topical Flea Treatment & Prevention is an effective tool in our flea control regimen. - Easy to apply the topical drops on your dog's skin along the backbone. - Our dogs have never had any skin irritation or other negative reactions with this product. - The 6 pack is a terrific value. I highly recommend this product.
K**R
Best price around beat all local vendors
There was no issues with hair loss, scratching caused by the product. Best price compared to local stores
H**Y
Kills fleas well normally, but some seasons fleas are particular difficult to control. This is a bad flea year for my area!!!
I have used this product for years on my dogs & can normally go as long as up to 8 weeks between doses. I have noticed that on some years (2014 & 2011) that the fleas are particular difficult to control. I know it is not due to this product not being effective because I have treated my yard with 2 different products that normally work very well within a 10 day period & even those products have made very little difference in the fleas. I have treated my dogs at 9 days & repeated again at 13 days. I am also using natural flea shampoo & topical sprays with essential oils. The fleas do die within 12 hours, but by that time my dog with allergies is a mess due to bites before they die. I am now seeing primarily very tiny fleas which tells me that I am achieving some control over the adult fleas. I dislike giving doses that close together, but that is what the insert recommends (actually every 7 days until controlled) for heavy flea infestations. One of my dogs has terrible flea allergies. He has been miserable & has been on prednisone & benadryl for over a month. I don't even like for him to be outdoors because they are so bad. I have to pick fleas off both dogs every time they step outside. I don't have any carpet in my home so I know they are not living in my house. It just seems that some years the fleas are just almost impossible to control. I am in Savannah, Ga. Last summer, the fleas were no problem at all. I did not even treat my lawn. I only gave Advantage every 6-8 weeks. The summer of 2011 was also a bad flea year. I'm not sure what is the cause, probably something to do with the weather or maybe they just have cyclic bad years (who knows). I thought this would be a mild year for fleas because the winter was so cold, but that apparently is not true. I have learned that unfortunately on bad flea years it will take a few months to get the fleas under control even using multiple products. Nothing much else you can do, but suffer until they are under control!!...............Update: After treating my yard with 2 different products within a month & treating my dogs with 3 doses (once every 10 days), the fleas appear to finally be under control. No fleas for 3 days!!! Allergic dog is finally getting some relief. Hopefully, I can now only treat my dogs monthly since I have gotten the severe flea infestation under control. It just takes a while to break the flea life cycle if you have a severe infestation..............UPDATE...Fleas are finally under control. Have not had to re-apply for 4 weeks. Just had a small flea on my allergic dog. Will re-apply today. Once you break the flea life cycle this will control the fleas. I buy the large dog size package & draw out the dosage for each dog with a blunt tip syringe. This is more cost effective & I have found that I can control the fleas by using a smaller dosage for my 30lb dog with allergies. The size package for his weight is a 2.5ml dose (weight range 21-55 lbs). He only weighs 30lbs & the weight limit is a very broad range for his size. The next smaller size range (10 to 20 lbs) is 1.0 ml so at approximately 0.5ml per 10 lbs, I don't feel he needs the entire 2.5ml dose & I have found that he does not. I normally am able to give him only 1.5 to 2.0 ml which will work fine once the severe infestation is under control. I don't like having to give chemicals to my dog & the less the better. He also has skin problems & the Advantage does seem to flare up his skin problems, so less is better. I am also able to give my cat a dose if he happens to pick up an untreated flea (he is an inside cat, but he will occasionally sneak out if he can). The Advantage is the same ingredients for dogs & cats (also confirmed with my vet), but the Advantix is NOT. DO NOT give Advantix to cats!
W**A
It works well
This is the only medicine actually works for my dog, I've tried 3 or 4 of other brands, and the same brand but oral pills, so far this one hits the target.
Y**A
No fleas!
Helps keep fleas off my little dog and it's easy to use after his bath. We live where there are squirrels and who knows what critters they carry! We have used these on all our dogs and used the cat version when we had cats.
H**T
Way better than Frontline
This stuff works very well. Frontline used to work however it's a no-go anymore. If you want to keep fleas off your dog, here you go
D**.
Adequate Flea Prevention, but Limited Coverage
I recently tried the Advantage II Medium Dog Flea Treatment for my furry friend, and while it does offer some level of protection, I can't help but feel it falls short in certain aspects. On the positive side, the convenience of a 6-month supply is appealing, and the application is relatively straightforward. My dog didn't seem bothered by it, and I appreciate the effectiveness in preventing fleas. However, my concerns arise when considering the limited scope of coverage. Advantage II is primarily designed for flea prevention, and while it does that job adequately, it doesn't provide protection against more serious illnesses transmitted by ticks. In my region, where tick-borne diseases are a significant concern, I opted for monthly pills with a prescription from my vet. The decision to switch to a different product was based on the need for comprehensive protection, especially considering the potential health risks associated with tick bites. While Advantage II may be suitable for areas where ticks are less prevalent, it didn't align with my dog's specific health requirements. In conclusion, if you're primarily dealing with flea prevention and live in an area where ticks are not a major concern, Advantage II could be a convenient option. However, for pet owners in regions with a higher risk of tick-borne diseases, it might be worth exploring alternative solutions with broader coverage, potentially involving a discussion with your vet for a prescription-based monthly treatment.
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